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	<title>Phyto-Remedies Blog &#187; selenium</title>
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		<title>Selenium Linked To Lower Skin Cancer Risk</title>
		<link>http://phyto-remedies.com/selenium-linked-to-lower-skin-cancer-risk/</link>
		<comments>http://phyto-remedies.com/selenium-linked-to-lower-skin-cancer-risk/#comments</comments>
		<pubDate>Wed, 06 May 2009 16:58:24 +0000</pubDate>
		<dc:creator>ted</dc:creator>
				<category><![CDATA[Skin Care]]></category>
		<category><![CDATA[selenium]]></category>
		<category><![CDATA[skin cancer]]></category>

		<guid isPermaLink="false">http://phyto-remedies.com/?p=96</guid>
		<description><![CDATA[This article appeared today in a post by NUTRAingredients.com:
&#8220;Higher blood levels of selenium may reduce the incidence of skin cancer by  about 60 per cent, according to a new study from Dutch and Australian  researchers.  Writing in Cancer Epidemiology, Biomarkers &#38; Prevention, the  researchers report that the mineral was associated with reduced [...]]]></description>
			<content:encoded><![CDATA[<p>This article appeared today in a post by NUTRAingredients.com:</p>
<p>&#8220;Higher blood levels of selenium may reduce the incidence of skin cancer by  about 60 per cent, according to a new study from Dutch and Australian  researchers.  Writing in <em>Cancer Epidemiology, Biomarkers &amp; Prevention</em>, the  researchers report that the mineral was associated with reduced risks of both  basal cell carcinoma (BCC) and squamous cell carcinoma (SCC).&#8221;<span id="more-96"></span></p>
<p>The FDA states:  Selenium may reduce the risk of certain cancers. Some scientific evidence  suggests that consumption of selenium may reduce the risk of certain forms of  cancer. However, FDA has determined that this evidence is limited and not  conclusive.</p>
<p>The Office of Dietary Supplements. part of NIH, states:</p>
<p><em>Selenium and cancer</em><br />
Observational studies indicate that death from  cancer, including lung, colorectal, and prostate cancers, is lower among people  with higher blood levels or intake of selenium [1-7]. In addition, the incidence of nonmelanoma skin cancer  is significantly higher in areas of the United States with low soil selenium  content [4]. The effect of  selenium supplementation on the recurrence of different types of skin cancers  was studied in seven dermatology clinics in the U.S. from 1983 through the early  1990s. Taking a daily supplement containing 200 μg of selenium did not affect  recurrence of skin cancer, but significantly reduced the occurrence and death  from total cancers. The incidence of prostate cancer, colorectal cancer, and  lung cancer was notably lower in the group given selenium supplements [<a class="fscopy_nounderline" href="#en41">8</a>].</p>
<p>Research suggests that  selenium affects cancer risk in two ways. As an anti-oxidant, selenium can help  protect the body from damaging effects of free radicals. Selenium may also  prevent or slow tumor growth. Certain breakdown products of selenium are  believed to prevent tumor growth by enhancing immune cell activity and  suppressing development of blood vessels to the tumor [<a class="fscopy_nounderline" href="#en42">9</a>].</p>
<p>The latest research, as stated in the nutraingredients article, was conducted at Queensland Institute of Medical Research, the University of Queensland, and  Maastricht University.</p>
<p><em>“Relatively high serum selenium concentrations are associated with an  approximately 60 per cent decrease in subsequent tumour incidence of both BCC  and SCC,”</em> wrote the researchers, <em>“whereas serum concentrations of  carotenoids or alpha-tocopherol are not associated with later skin cancer  incidence.”</em></p>
<p>The American Institute for Cancer Research has numerous articles about selenium and cancer.<em> http://www.aicr.org/site/DocServer/ProstateMC.pdf?docID=1641<br />
</em></p>
<p>Sources<em>:  www.nutraingredients.com;   http://ods.od.nih.gov/factsheets/selenium.asp;   www.aicr.org;<br />
</em></p>
<p><em><br />
</em></p>
<ol class="fscopy">
<li class="fscopy"><a class="fscopy_nounderline" name="en34"></a>Russo MW, Murray SC,  Wurzelmann JI, Woosley JT, Sandler RS. Plasma selenium levels and the risk of  colorectal adenomas. Nutr Cancer 1997;28:125-9. <span class="fsCopy">[</span><a class="fscopy" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;list_uids=%209290116&amp;dopt=Abstract">PubMed  abstract</a><span class="fsCopy">]</span></li>
<li class="fscopy"><a class="fscopy_nounderline" name="en35"></a>Patterson BH and  Levander OA. Naturally occurring selenium compounds in cancer chemoprevention  trials: A workshop summary. Cancer Epidemiol Biomarkers Prev 1997;6:63-9. <span class="fsCopy">[</span><a class="fscopy" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;list_uids=8993799&amp;dopt=Abstract">PubMed  abstract</a><span class="fsCopy">]</span></li>
<li class="fscopy"><a class="fscopy_nounderline" name="en36"></a>Knekt P, Marniemi J,  Teppo L, Heliovaara M, Aromaa A. Is low selenium status a risk factor for lung  cancer? Am J Epidemiol 1998;148:975-82. <span class="fsCopy">[</span><a class="fscopy" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;list_uids=%209829869&amp;dopt=Abstract">PubMed  abstract</a><span class="fsCopy">]</span></li>
<li class="fscopy"><a class="fscopy_nounderline" name="en37"></a>Fleet JC. Dietary  selenium repletion may reduce cancer incidence in people at high risk who live  in areas with low soil selenium. Nutr Rev 1997;55:277-9. <span class="fsCopy">[</span><a class="fscopy" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;list_uids=9279064&amp;dopt=Abstract">PubMed  abstract</a><span class="fsCopy">]</span></li>
<li class="fscopy"><a class="fscopy_nounderline" name="en38"></a>Shamberger RJ. The  genotoxicity of selenium. Mutat Res 1985;154:29-48. <span class="fsCopy">[</span><a class="fscopy" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;list_uids=3923345&amp;dopt=Abstract">PubMed  abstract</a><span class="fsCopy">]</span></li>
<li class="fscopy"><a class="fscopy_nounderline" name="en39"></a>Young KL and Lee PN.  Intervention studies on cancer. Eur J Cancer Prev 1999;8:91-103. <span class="fsCopy">[</span><a class="fscopy" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;list_uids=10335455&amp;dopt=Abstract">PubMed  abstract</a><span class="fsCopy">]</span></li>
<li class="fscopy"><a class="fscopy_nounderline" name="en40"></a>Burguera JL, Burguera  M, Gallignani M, Alarcon OM, Burgueera JA. Blood serum selenium in the province  of Merida, Venezuela, related to sex, cancer incidence and soil selenium  content. J Trace Elem Electrolytes Health Dis 1990;4:73-7. <span class="fsCopy">[</span><a class="fscopy" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;list_uids=2136228&amp;dopt=Abstract">PubMed  abstract</a><span class="fsCopy">]</span></li>
<li class="fscopy"><a class="fscopy_nounderline" name="en41"></a>Combs GF, Jr., Clark  LC, Turnbull BW. Reduction of cancer risk with an oral supplement of selenium.  Biomed Environ Sci 1997;10:227-34. <span class="fsCopy">[</span><a class="fscopy" href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;list_uids=%209315315&amp;dopt=Abstract">PubMed  abstract</a><span class="fsCopy">]</span></li>
<li class="fscopy"><a class="fscopy_nounderline" name="en42"></a>Combs GF, Clark LC,  Turnbull BW. An analysis of cancer prevention by selenium. BioFactors 14 2001;  153-9.</li>
</ol>
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